Diethyl (4-Isopropylbenzyl)phosphonate

Diethyl (4-Isopropylbenzyl)phosphonate - Names and Identifiers

Name	diethyl [4-(1-methylethyl)benzyl]phosphonate
Synonyms	LogP 4-(DIETHYLPHOSPHONOMETHYL)CUMENE DIETHYL (4-ISOPROPYLBENZYL)PHOSPHONATE Diethyl (4-Isopropylbenzyl)phosphonate diethyl [4-(1-methylethyl)benzyl]phosphonate 1-(DIETHYLPHOSPHONOMETHYL)-4-ISOPROPYLBENZENE (4-ISOPROPYLBENZYL)PHOSPHONIC ACID DIETHYL ESTER Phosphonic acid, [[4-(1-methylethyl)phenyl]methyl]-, diethyl ester (9CI) 4-(Diethylphosphonomethyl)cumene1-(Diethylphosphonomethyl)-4-isopropylbenzene(4-Isopropylbenzyl)phosphonic Acid Diethyl Ester
CAS	77237-55-9
InChI	InChI=1/C14H23O3P/c1-5-16-18(15,17-6-2)11-13-7-9-14(10-8-13)12(3)4/h7-10,12H,5-6,11H2,1-4H3

Diethyl (4-Isopropylbenzyl)phosphonate - Physico-chemical Properties

Molecular Formula	C14H23O3P
Molar Mass	270.3
Density	1.044g/cm³
Boling Point	363.4°C at 760 mmHg
Flash Point	187.2°C
Vapor Presure	3.79E-05mmHg at 25°C
Appearance	clear liquid
Color	Colorless to Almost colorless
Storage Condition	2-8℃
Refractive Index	1.4900-1.4950

Diethyl (4-Isopropylbenzyl)phosphonate - Introduction

diethyl [4-(1-methyllethyl) benzyl]phosphonate is an organophosphorus compound with a chemical formula of C14H21O3P and a molecular weight of 270.29. It is a colorless to yellow liquid with a special odor.

This compound is often used as an intermediate in organic synthesis, especially in pharmaceutical synthesis. It has good solubility and stability, and can be used as a catalyst or reagent for organic synthesis reactions, such as phosphonic acid acetal reaction, Staudinger reduction reaction, etc.

diethyl [4-(1-methyllethyl) benzyl]phosphonate can be prepared by reacting isopropyl benzyl alcohol with diallyl diethylaminophosphonate under anhydrous conditions. During the reaction, attention should be paid to the control of temperature and reaction time to ensure a higher yield of the product.

For safety information, diethyl [4-(1-methyllethyl) benzyl]phosphonate may cause eye, skin and respiratory tract irritation. During operation, it is recommended to wear protective glasses, protective gloves and breathing apparatus. Avoid direct contact and try to operate in a well-ventilated laboratory. In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical help.

Last Update：2024-04-09 20:02:46